1. "St. Louis Blues (W.C. Handy Cover)" by The Isley Brothers
Before the hockey team, this blues staple set in the city of St. Louis, Missouri, was originally composed by W.C. Handy at the turn of the 20th century and tells the tale of a spouse in dire straits over the absence of their partner. Although the venerated French monarch is not directly referenced to in the song, the city's name gives testimony to the grand tradition of invoking the intercession of a saint particular to a founding community's devotion by dedicating the place after them (many American examples are listed here, here and here). In regards to the song, there exist many different covers and this one by the Isley Brothers appears in the same album as their hit "Shout" and their take on "When the Saints Go Marching In".
2. "Dao of St. Paul" Third Eye Blind
From the 2009 album Ursa Major by alternative rockers Third Eye Blind, the protagonist of this song feigns indifference towards a woman he still has feelings for in an effort to exercise the Dao (or Way) of St. Paul, possibly alluding to his letter to Philippians which was penned in prison and includes the words "Rejoice in the Lord always. I will say it again: rejoice!". And though I don't pretend to know much of anything concerning Daoism or any other Chinese philosophy, this podcast I recently listened to served as an approachable introduction.
3. "Saints of Los Angeles" by Mötley Crüe
Serving as comeback hit for glam metal veterans Mötley Crüe, the title track from the band's ninth album got it right about saints being persons worthy of imitation but missed the mark with regards to the behaviors that should be emulated. The good news is that the city has a new auxiliary bishop who does an excellent job in the leading-people-to-sainthood department.